Carmen Buchrieser is Professor at the Institut Pasteur, in Paris, France. She obtained her PhD from the University of Salzburg in Austria. After conducting postdoctoral trainings in the USA and the Institut Pasteur in Paris, she was appointed in 2008 director of the Unit “Biology of Intracellular Bacteria” at the Institut Pasteur, Paris, France. She is a member of the German Academy of Science, Leopoldina (2013), an elected member of EMBO (2013), of the Academia Europea (2016), the American Academy of Microbiology (2013) and the European Academy of Microbiology (2016). Her major research interest is to understand how bacteria cause disease: what are the genetic factors conferring bacterial virulence, how do they evolve, what are the mechanisms by which they allow subverting host functions and more generally how do human pathogens emerge. She uses Legionella as a model, as these bacteria are at the crossroad between an environmental bacterium (parasite of protozoa) and a human pathogen (replicating in alveolar macrophages). The projects of her laboratory are focused on the identification and study of virulence factors of Legionella pneumophila and L. longbeachae, with particular emphasis on their functions, their regulation and the mechanisms leading to their acquisition and their evolutionary origin. Recently she developed a new research topic, the study how Legionella is targeting organelles in the host cell. These studies have increased our interest in the analyses of the host response to infection by an intracellular pathogen and to identify he host pathways that are necessary to fight infection.